Under-Eye Mesotherapy

Under-eye mesotherapy is a medical aesthetic treatment in which ingredients suited to the delicate under-eye area are injected into the skin in very small amounts to support the quality, hydration and vitality of the thin skin beneath the eyes. It may be considered for concerns such as a tired appearance, fine lines, dryness and thinning of the under-eye skin. For people considering under-eye mesotherapy in Izmir, treatment is planned by evaluating the structure of the under-eye skin, the cause of the concern and personal expectations together.

What Is Under-Eye Mesotherapy?

Mesotherapy is a method in which active ingredients that nourish and support the skin are delivered directly into the targeted layer of the skin through micro-injections. Under-eye mesotherapy is a version of this approach specifically adapted to the under-eye area, the part of the face with the thinnest skin.

The skin under the eyes is much thinner than on other areas of the face; it has fewer oil glands and is in constant motion due to facial expressions. For this reason, dryness, thinning, fine lines and a tired appearance are noticed earlier in this area as a result of age, lack of sleep, sun exposure and environmental factors. The aim of under-eye mesotherapy is to support the quality of this thin skin and contribute to a more rested and vibrant appearance.

The products used in under-eye mesotherapy are chosen with the sensitivity of the area in mind. Not every product used on other areas of the face is suitable for the under-eye area.

Ingredients Used in Under-Eye Mesotherapy

At our clinic, products containing one or more of the following ingredients are preferred for under-eye mesotherapy, depending on the needs of the skin. Which ingredient or combination will be used is determined after a consultation.

Ingredient Intended Effect Under the Eyes
Polynucleotides (salmon DNA) Supporting the repair and renewal processes of thin skin
Succinic acid Antioxidant support and vitality for a tired appearance
Hyaluronic acid Supporting hydration balance and skin elasticity
Peptides Supporting skin quality and firmness from different angles
Amino acids Providing the building blocks needed for collagen and elastin production

Polynucleotides (Salmon DNA)

Polynucleotides are purified chains derived from salmon, made up of the building blocks of DNA. They are considered to have a biostimulatory effect aimed at supporting the skin’s natural repair and renewal processes. They may be preferred for supporting skin thickness, elasticity and texture in thin and tired areas such as under the eyes. For more information about this ingredient, you can visit our salmon DNA and Rejuran pages.

Succinic Acid

Succinic acid is a natural organic acid involved in the energy production cycle of cells. It is used in mesotherapy products for its antioxidant properties, to support cells against oxidative stress and to contribute to cellular energy metabolism. Under the eyes, the aim is to support vitality against a tired and dull appearance.

Hyaluronic Acid

Hyaluronic acid is a molecule naturally found in the body that can hold many times its own weight in water. In under-eye mesotherapy, hyaluronic acid is applied at a low density not as a filler, but to support the hydration balance and elasticity of thin and dry under-eye skin. You can also find information about hydration-focused treatments on our skin hydration injection page.

Peptides

Peptides are short chains of amino acids that act as signals in various biological processes in the skin. The peptides found in under-eye products aim to support skin firmness, texture and overall quality. Some peptides are also thought to have supportive effects on puffiness related to fluid retention and darkness under the eyes.

Amino Acids

Amino acids are the building blocks of the skin’s supporting proteins, such as collagen and elastin. In under-eye mesotherapy, amino acids aim to provide the building blocks the skin needs in its own renewal process. They are usually found in combination products together with hyaluronic acid and peptides.

Which Concerns Can Under-Eye Mesotherapy Be Considered For?

  • Tired and dull appearance: Loss of skin quality that gives a sleepless, tired look under the eyes
  • Fine lines: Superficial lines related to dryness and thinning
  • Dryness and thinning: Moisture loss and under-eye skin that thins with age
  • Mild darkness: A mild bruised look caused by visible blood vessels beneath thin skin
  • Reduced skin quality: Under-eye skin with reduced elasticity and firmness

Under-Eye Dark Circles and Mesotherapy

Under-eye dark circles can have different causes. For dark circles caused by visible blood vessels beneath thin skin, under-eye mesotherapy that supports skin quality may be helpful. However, pigmentation treatments may be more suitable for darkness caused by pigmentation, and methods such as under-eye light filler for shadowing caused by under-eye hollowness. An examination is important to distinguish the cause of the dark circles. Details can be found on our under-eye dark circles page.

Eye Bags and Mesotherapy

Eye bags are often related to the forward displacement of fat tissue or skin laxity. Under-eye mesotherapy does not remove prominent eye bags; however, it can be planned as a complementary method that supports the quality of the skin around the bags and the overall appearance. For options targeting eye bags, you can visit our eye bags treatment page.

Personalized Treatment

Every individual’s skin and skin structure are unique. Therefore, Under-Eye Mesotherapy should be personalized for each person.

Sterile Clinical Environment

Under-Eye Mesotherapy must be performed under the supervision of a specialist physician and in a sterile clinical environment.

Treatment Tailored to Your Needs

In our clinic, the number of sessions is customized specifically for you, both for Under-Eye Mesotherapy and our other treatments.

What Is the Difference Between Under-Eye Mesotherapy and Under-Eye Light Filler?

These two treatments are often confused. Under-eye light filler is a volume treatment aimed at reducing the appearance of shadows by filling the under-eye hollow. Under-eye mesotherapy does not add volume; it focuses on supporting skin quality, hydration and vitality. In people who have both hollowness and skin quality concerns, the two methods may be planned together.

For other non-surgical options for the eye area, you can visit our non-surgical eye area aesthetics page, and for fine lines, our eye wrinkle treatment page.

Who Is Under-Eye Mesotherapy Suitable For?

It may be considered for adults who notice a tired appearance, dryness, fine lines, thinning or mild darkness caused by thin skin under the eyes. It may not be sufficient on its own in cases of significant under-eye hollowness, advanced eye bags or pigmentation-related darkness; different methods or combined planning may be considered in these situations. Before treatment, the condition of the under-eye skin can be assessed with a skin analysis.

Treatment may be postponed if there is an active infection or an ongoing skin condition in the treatment area. Pregnancy, breastfeeding, autoimmune diseases, allergies (especially allergy to fish products), use of blood-thinning medication, eye diseases and previous aesthetic treatments should be shared with the physician during the assessment.

How Is Under-Eye Mesotherapy Performed?

Before the procedure, the under-eye skin and the cause of the concern are assessed. After the area is cleansed, a numbing cream may be applied to improve comfort. The selected product is applied to the appropriate layer of the under-eye skin in small amounts through many tiny points, using very fine needles or a cannula. The treatment is usually short.

Under-eye mesotherapy is often applied in several sessions planned a few weeks apart, followed by maintenance sessions depending on the condition of the skin. The number of sessions, intervals and the product used vary from person to person.

What Can Be Expected After Treatment?

Because the under-eye skin is thin, small bumps, mild swelling, redness or bruising may appear at the injection points after treatment. These effects usually subside within a few days. It is recommended to avoid make-up on the first day, avoid applying pressure to or rubbing the area, avoid saunas, Turkish baths and intense exercise, and protect the skin from the sun. Following the aftercare instructions given by the physician is important.

When Are Results Visible and How Long Do They Last?

Vitality related to hydration support may become noticeable after the first sessions, while changes in skin quality develop gradually as the sessions progress. Under-eye mesotherapy is not a permanent treatment. How long the effect remains noticeable varies depending on age, skin structure, sleep patterns, lifestyle, sun exposure and the product used. During follow-up, the under-eye area can be reassessed to determine whether maintenance sessions are needed.

Under-Eye Mesotherapy Prices in Izmir

It is not accurate to give a single price for under-eye mesotherapy without a personal assessment. The cost may vary depending on the product and ingredients used, the number of sessions planned and the plan created according to the person’s needs.

For those who would like to learn about the price and scope of under-eye mesotherapy in Izmir, the under-eye skin should first be assessed. After the consultation, a personalised plan can be created and information about the scope of treatment and pricing can be provided.

Under-Eye Mesotherapy in Izmir

Uzm. Dr. Ecem Cantürk Nazlı provides dermatology and medical aesthetic services at her clinic in Alsancak, Izmir. In a thin and delicate area such as under the eyes, choosing the right product, applying it at the appropriate depth and amount, and correctly identifying the cause of the concern are important.

If you are considering under-eye mesotherapy in Izmir, whether it is suitable for you and which ingredients may be preferred can be determined after a consultation. Results vary from person to person; each treatment should be approached according to the person’s skin structure and needs.

Frequently Asked Questions

What is under-eye mesotherapy?

It is a medical aesthetic treatment in which ingredients such as polynucleotides, hyaluronic acid, peptides, amino acids and succinic acid are applied through micro-injections to support the quality, hydration and vitality of the thin skin under the eyes.

Is under-eye mesotherapy a filler?

No. Under-eye mesotherapy does not add volume; it supports skin quality. The treatment aimed at filling under-eye hollows is under-eye light filler.

Does under-eye mesotherapy help with dark circles?

It may be helpful for mild dark circles caused by visible blood vessels beneath thin skin by supporting skin quality. Different methods may be needed for darkness caused by pigmentation or hollowness.

Is salmon DNA used in under-eye mesotherapy?

Yes. Polynucleotides (salmon DNA) are among the ingredients used to support the skin’s repair and renewal processes in thin and tired areas such as under the eyes.

How many sessions of under-eye mesotherapy are needed?

The number of sessions is determined according to the condition of the skin. A few sessions planned a few weeks apart, followed by maintenance sessions, are commonly recommended.

Is under-eye mesotherapy painful?

The treatment is performed with very fine needles, and a numbing cream may be used beforehand if needed. The level of discomfort varies from person to person but is tolerable for most people.

Does bruising occur after under-eye mesotherapy?

Because the under-eye skin is thin, mild bruising or swelling may occur. These effects usually resolve within a few days.

Can under-eye mesotherapy be combined with other treatments?

Yes. Depending on the need, a treatment plan can be created together with methods such as under-eye light filler, Botox or laser treatments. The order and intervals of treatments are determined by the physician.

Overall Assessment

Under-eye mesotherapy is a treatment aimed at supporting the quality, hydration balance and vitality of the thin skin under the eyes with ingredients such as polynucleotides (salmon DNA), succinic acid, hyaluronic acid, peptides and amino acids. It does not add volume like a filler; it may be considered in suitable patients for a tired appearance, dryness, fine lines and mild darkness caused by thin skin. Since under-eye concerns have different causes, the choice of the right method should be based on an examination.

At Uzm. Dr. Ecem Cantürk Nazlı’s clinic in Alsancak, Izmir, whether under-eye mesotherapy is suitable for you can be planned after an under-eye assessment. You can book a consultation for detailed information and a personal assessment.

İçerik Sorumlusu ve Tıbbi Denetim

TIBBİ UZMAN

Uzm. Dr. Ecem Cantürk Nazlı — Dermatoloji Uzmanı – Medikal Estetik

Uzm. Dr. Ecem Cantürk Nazlı, Hacettepe Üniversitesi Tıp Fakültesi İngilizce programından mezun olmuş; dermatoloji, lazer uygulamaları ve medikal estetik alanlarında 10 yılı aşkın mesleki deneyim edinmiştir.

Ulusal ve uluslararası eğitimlerle mesleki çalışmalarını sürdüren Dr. Ecem, 2022 yılından bu yana İzmir Alsancak’taki özel muayenehanesinde hastalarını kabul etmektedir.

Hakkımda

Under-Eye Mesotherapy içeriği Uzm. Dr. Ecem Cantürk Nazlı tarafından hazırlanmış ve tıbbi doğruluk açısından incelenmiştir.

Yayınlanma: October 2026. Bu sayfa bilgilendirme amaçlıdır, tıbbi tavsiye yerine geçmez.